Which apparatus is used for disintegration test?

Which apparatus is used for disintegration test?

Disintegration Tester is a solid state instrument designed for the accurate estimation of disintegration time of tablets as per IP/USP standards. The instrument is designed to test two batches of six tablets, simultaneously. The unit is extremely useful for pharmaceutical industries.

Which USP apparatus is modification of disintegration apparatus?

Rotating Cylinder Apparatus (USP Apparatus 6):- This is a modification of the basket apparatus (USP Apparatus 1) with the basket being replaced by a stainless steel cylinder. The sample is again usually a transdermal delivery system attached to the outside of the cylinder.

What is the principle of disintegration test?

Disintegration testing measures the ability of a tablet to break down into smaller particles or granules to allow the active drug to be absorbed into the body.

What is 5.3 disintegration test?

11. This test is provided to determine whether tablets or capsules disintegrate within the prescribed time. 12. when placed in a liquid medium under the experimental conditions presented below.

How do you use disintegration test apparatus?

Method. Put one tablet into each tube, suspend the assembly in the beaker containing 0.1 M hydrochloric acid and operate without the discs for 2 hours, unless otherwise stated in the individual monograph. Remove the assembly from the liquid.

What is disintegration Slideshare?

If any residue remains, it must have a soft mass with no hard core .  Complete disintegration is a state in which any residue remain is a soft mass having no palpable firm core except fragments of insoluble coating remaining on the screen of the apparatus.

What is the USP apparatus 3?

USP Apparatus 3 (reciprocating cylinder) is a very versatile device for the in vitro assessment of release characteristics of solid oral dosage forms, because it enables the product to be subjected to different dissolution media and agitation speeds in a single run.

What is complete disintegration?

Complete disintegration is defined as that state in which any residue of the unit, except fragments of insoluble coating or capsule shell, remaining on the screen of the test apparatus or adhering to the lower surface of the discs, if used, is a soft mass having no palpably firm core. Apparatus.

What is tablet disintegration apparatus?

Tablet Disintegration Test Apparatus is microprocessor based instrument designed to be used by pharmaceutical industry for accurate determination time of tablets and capsules as per IP/BP/USP standards, The Disintegration Test Apparatus helps in evaluation of disintegration capability of formulations (ex: tablets) and …

What is DT in pharma?

Disintegration time is the time required for a dosage form to break up in to granules of specified size (or smaller) under carefully specified conditions. In other words DT (disintegration time) is measuring the break down of a dosage form and dissolution is measuring the drug being solubilized in the media.

What is a complete disintegration?

What is disintegration test PPT?

Disintegration test (U.S.P.) :  For a drug to be readily available to the body , it must be in solution.  For most tablets, the first important step toward solution is break down of the tablet into smaller particles or granules, a process called disintegration. 3/13/20152.

How to test the disintegration capability of tablets?

To test the disintegration capability of tablets and capsules as per the pharmacopoeial standards like USP, BP, and IP. If for instance the disintegration time within the set of samples varies or is too high or low then it wouldn’t correspond to the pharmacopeial standards. ii.

Why do you need a disintegration tester instrument?

Below are some of the main reasons why you need a disintegration tester instrument: i. To test the disintegration capability of tablets and capsules as per the pharmacopoeial standards like USP, BP, and IP.

What is a disintegration test?

Disintegration test – It is a process of knowing the time it takes for a solid dosage form to completely disintegrate. Dissolution – It the process where solid substances enter a solvent, forming a solution.

Does disintegration imply solution of the dosage unit?

For the purpose of this test, disintegration does not imply complete solution of the dosage unit or even of its active constituent.