What tramadol is used for?

What tramadol is used for?

Tramadol is used to relieve moderate to moderately severe pain, including pain after surgery. The extended-release capsules or tablets are used for chronic ongoing pain.

How much tramadol can you take at once?

Adults—At first, 25 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 400 mg per day. Children younger than 12 years of age—Should not be used in these patients.

Is tramadol OK for elderly?

However, elderly patients are more likely to have unwanted side effects (eg, constipation, lightheadedness, dizziness, or fainting, stomach upset, weakness) and age-related liver, kidney, heart, or lung problems, which may require caution and an adjustment in the dose for patients receiving tramadol.

What is tramadol hydrochloride?

Tramadol Hydrochloride is a synthetic codeine analogue, Tramadol Hydrochloride has central analgesic properties with effects similar to opioids, such as morphine and codeine, acting on specific opioid receptors.

What is the mechanism of action of(R-R)-tramadol?

(R,R)-tramadol is a 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. It has a role as a delta-opioid receptor agonist,…

How much plasma clearance from tramadol is normal?

The plasma clearance was 6.4 mL/min/kg in males and 5.7 mL/min/kg in females following a 100 mg IV dose of tramadol. Following a single oral dose, and after adjusting for body weight, females had a 12% higher peak tramadol concentration and a 35% higher area under the concentration-time curve compared to males.

What is the difference between codeine and tramadol?

Tramadol is a synthetic codeine analogue, Tramadol has central analgesic properties with effects similar to opioids, such as morphine and codeine, acting on specific opioid receptors.