What is the survival rate of osteosarcoma in children?

What is the survival rate of osteosarcoma in children?

The overall 5-year survival rate for children ages 0 to 14 with osteosarcoma is 68%. For teens ages 15 to 19, the 5-year survival rate is 67%. If osteosarcoma is diagnosed and treated before it has spread outside the area where it started, the general 5-year survival rate for people of all ages is 74%.

What is the primary site of osteosarcoma in children?

Osteosarcoma commonly occurs in the long bones of the extremities near the metaphyseal growth plates. The most common sites are the femur (42%, with 75% of tumors in the distal femur), the tibia (19%, with 80% of tumors in the proximal tibia), and the humerus (10%, with 90% of tumors in the proximal humerus).

How is osteosarcoma treated in children?

Treatment of osteosarcoma in children includes chemotherapy (the use of medical drugs to kill cancer cells and shrink the cancer), followed by surgery (to remove cancerous cells or tumors), and then more chemo (to kill any remaining cancer cells and minimize chances of the cancer coming back).

Can you survive metastatic osteosarcoma?

Five years overall survival in osteosarcoma patients is around 70%, although in patients with metastatic disease it is only 10-30%. The objective of this study was to analyze overall survival and prognostic factors in a group of patients with metastatic osteosarcoma treated with surgical removal of the lung metastases.

What is pediatric osteosarcoma?

Osteosarcoma (also known as osteogenic sarcoma) is a tumor that almost always occurs in a bone, most commonly near the growth plates around the knee, arms, legs and pelvis. It is the most common type of pediatric bone tumor.

How long does osteosarcoma take to grow?

The vast majority of osteosarcomas are so-called “random cases”, where no specific causes or predisposing risk factors can be identified. In young people, the development of the tumour appears to be in some way related to periods in life with rapid bone growth, hence the average for tumour development is 14-16 years.

What is the most common site of osteosarcoma?

Where does osteosarcoma start?

  • Most tumors develop in the bones around the knee, either in the lower part of the thigh bone (distal femur) or the upper part of the shinbone (proximal tibia).
  • The upper arm bone close to the shoulder (proximal humerus) is the next most common site.

Is osteosarcoma serious?

Complications of osteosarcoma and its treatment include: Cancer that spreads (metastasizes). Osteosarcoma can spread from where it started to other areas, making treatment and recovery more difficult. Osteosarcoma that spreads most often spreads to the lungs and to other bones.

How long can you live with metastatic osteosarcoma?

Osteosarcoma. Around 40 out of 100 people (around 40%) survive their cancer for 5 years or more after diagnosis.

What’s the survival rate of osteosarcoma?

Osteosarcoma 5-year relative survival rates

SEER stage 5-year relative survival rate
Localized 74%
Regional 66%
Distant 27%
All SEER stages combined 60%

How do you know if osteosarcoma is spreading?

A CT scan of the chest may be done to see if cancer has spread to the lungs. Bone scan: A bone scan can help show if a cancer has spread to other bones. This test is useful because it can show all of the bones in the body at once.

What are the treatment options for osteosarcoma in children?

Joint replacement if your child’s osteosarcoma is located on or near his knee, hip or shoulder. If your child is still growing, a modified joint replacement that can be expanded as your child grows, may be used. Allograft (cadaver bone) if your child’s tumor is in the middle of an arm or leg bone.

How is osteosarcoma (OS) defined?

Abstract Osteosarcoma (OS), the most common type of primary malignant bone tumor, is defined by the presence of malignant mesenchymal cells producing osteoid or immature bone. The peak incidence of the most frequent type of OS, i.e., high-grade central OS, occurs in the second decade of life during the adolescent growth spurt.

What are the treatment options for osteosarcoma oesophagitis (OS)?

OS can be treated with surgery, radiotherapy, and chemotherapy. There is a clear need for newer effective agents for patients with OS, especially for patients who afflicted with metastatic and recurrence tumor. Monoclonal antibodies directed against OS may prove useful as treatment, either for drug delivery or for radiopharmaceuticals.

What is the prevalence of bone cancer in children?

In general, bone tumors in children are rare, with an estimated 8.7 per million in children younger than 20 years of age,[4] representing 650–700 new bone cancer patients a year.