What is R-CHOP chemo used for?
What is R-CHOP chemo used for?
R-CHOP is used to treat non-Hodgkin lymphoma (NHL). It is best to read this information with our general information about chemotherapy and the type of cancer you have. CHOP comes from the initials of the drugs used: R – rituximab.
What drugs are in R EPOCH?
An abbreviation for a chemotherapy combination used to treat certain types of non-Hodgkin lymphoma. It includes the drugs rituximab, etoposide phosphate, prednisone, vincristine sulfate (Oncovin), cyclophosphamide, and doxorubicin hydrochloride (hydroxydaunorubicin).
Will I lose my hair with R-CHOP?
Hair loss: You will have total hair loss, including the hair on your head as well as eyebrows, eyelashes, and body hair. Usually, this starts two to three weeks after treatment, but it is temporary and your hair should return after treatment.
How do you feel after R-CHOP chemotherapy?
Any side effects are most likely to happen when you first start R-CHOP therapy. You may be more likely to get them if you’re also receiving radiation or another treatment. Common side effects may include: Fever, muscle aches, headache, and shivers from low white blood cell counts.
How effective is R epoch?
The patients received DA-EPOCH-R administered with CNS prophylaxis for six cycles. Primary endpoints included event-free (EFS) and overall survival (OS). The overall response rate was 87 percent, and 74 percent achieved a complete response. The 48-month EFS and OS were 71 percent and 77 percent respectively.
What is the R-EPOCH-R chemotherapy regimen?
R-EPOCH, also referred to as EPOCH-R, is a combination chemotherapy regimen used to treat certain malignancies, especially certain types of aggressive non-Hodgkin lymphoma . The drug regimen consists of the following agents:
What is EPOCH chemotherapy for non-Hodgkin lymphoma?
The EPOCH chemotherapy regimen is the gold standard for treatment of all B-cell non-Hodgkin lymphoma types. These include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, and mantle cell lymphoma.
How is DA-EPOCH-R administered?
Outpatient DA-EPOCH-R may require a clinic visit on Day 1 and 5, but Days 2, 3, and 4 can be administered at home using a small, portable infusion pump. DA-EPOCH-R is typically repeated every 21 – 28 days.
What are the results of the NCI DA-EPOCH-R trial?
Results of a single arm trial with DA-EPOCH-R, conducted by researchers at the NCI, which followed 51 patients for a period of up to 14 years, were published in the April 11, 2013, issue of the New England Journal of Medicine. Fifty-one patients with untreated primary mediastinal B-cell lymphoma were included in this study.